PARTNERS

Our partners are leaders in their fields and pioneers in research on Down  syndrome and Alzheimer’s disease.

Florence Lai, MD



Dr. Florence Lai of Harvard University and Massachusetts General Hospital is the lead Massachusetts researcher in a multi-center, multi-year study funded by the National Institutes of Health.


Dr. Lai said the study is seeking “biomarkers” that may predict the onset of Alzheimer’s disease and enable researchers to learn more about its link with Down syndrome.


“For my many wonderful patients with Down syndrome who have genuinely brightened the lives of their families and friends (including me), I dedicate my professional energies to eradicate Alzheimer disease from their lives.”

— Florence Lai, MD

Herminia Diana Rosas, MD


Dr. Rosas and her team have focused on the development of biomarkers to study neurodegenerative diseases, including Alzheimer disease in Down syndrome, in order to better define biological onset, track progression, understand the relationship between genetic changes and the clinical symptoms, and to apply innovative neuroimaging approaches to both understanding the regions of the brain that are first affected, how that pattern changes over time and how those relate to clinical symptoms.


She and her team have begun to develop models that could explain clinical heterogeneity and disease progression variability. These models are critical for both understanding the disease and how it affects individuals and for helping develop and bring therapies to the DS population.


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